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Important advances in next generation genome editing tools for Huntington’s Disease

Work with genome editing techniques (zinc fingers and CRISPR) brings these tools closer to use in HD clinical trials Recent days have seen a slew...

Rhenovia files patents for new treatment of Huntington’s disease based on its innovative biosimulation...

Rhenovia’s discovery of flagship drug candidate RHEDAR(TM) through biosimulation brings further proof of the high efficiency of this novel method for developing drugs to...

Vaccinex, Inc. announces the initiation of a Phase 2 clinical trial of its investigational...

Vaccinex, Inc. announced today that it has initiated a Phase 2 clinical trial to assess the safety, tolerability and efficacy of anti-semaphorin 4D antibody...

Rottura della segnalazione cellulare porta alla neurodegenerazione

I ricercatori del RIKEN Brain Science Institute in Giappone, in collaborazione con la Juntendo University e la Japan Science and Technology Agency, hanno scoperto...

Shooting the messenger with single-stranded RNA gene silencing

After huge leaps forward in recent years, we're edging ever closer to human trials of huntingtin lowering or 'gene silencing' as a potential treatment...

Annunciato trial clinico per la Malattia di Huntington: farmaco per l’ abbassamento dei livelli...

Una nuova sperimentazione clinica appena annunciata per il 2015 ha l' obiettivo di testare una terapia di “abbassamento dei livelli di huntintina”, chiamata oligonucleotide...

An Interview with Dr. Nancy Wexler: Discovering the Huntington Disease Gene

One morning in 1968, Dr. Nancy Wexler’s mother, Leonore Wexler, had jury duty in downtown Los Angeles. As Leonore crossed the street on the way...

Huntington’s disease trial test is ‘major advance’

Scientists say they may have found the world's first blood test that predicts when someone at risk is likely to get Huntington's disease and...

Prana announces results of Reach2HD trial of PBT2 for Huntington’s disease

The results are in from the Reach2HD study, which was designed to test the experimental drug PBT2 for early and mid-stage Huntington's disease. The...
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Scientists tackle Huntington’s disease by targeting mutant gene

Huntington's disease is an inherited, neurodegenerative disorder that usually appears in mid-adult life and leads to uncoordinated body movements and cognitive decline. The disease...

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Huntington’s Disease Therapeutics Conference 2016 – day 1

If it’s February, that means the the world’s leading scientists are converging on Palm Springs for the annual HD therapeutics conference! Monday evening - updates...

What the ‘big neurodegeneration breakthrough’ means for Huntington’s disease

Many people in the Huntington's disease community have noticed reports highlighting a recent study from the University of Leicester, which the BBC claimed "could...

Study reveals brain cells’ weakest links

Patients with degenerative conditions such as Huntington’s disease and Alzheimer’s disease could be helped by research that shows for the first time why their...

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