Moving toward a potential treatment: Isis, CHDI researchers outline upcoming Huntington’s disease gene-silencing trial

Scientific research and clinical trials aren’t glamorous, but they are the meat and potatoes of effective treatments and perhaps ultimately a cure for Huntington’s...

Update on molecular therapies for Huntington’s disease

I am flying back from the EHDN meeting which is taking place in Stockholm, Sweden. As usual, I met with many colleagues, caregivers and...

Protein Subunit Found to Rescue Afflicted Neurons in Huntington’s Disease

Novel co-culturing method creates functional circuits modeling fatal brain condition, provides clues to potential new treatment approach Using an experimental co-culture approach in which two...

Altered brain mechanisms of emotion processing in pre-manifest Huntington’s disease

Abstract Huntington's disease is an inherited neurodegenerative disease that causes motor, cognitive and psychiatric impairment, including an early decline in ability to recognize emotional states...

Novel Gene Therapy Drug for Huntington’s Disease

Data from Vybion on a novel treatment for Huntington's disease has been published in the Journal of Neurodegenerative diseases. The published study (http://www.hindawi.com/journals/jnd/2016/7120753/) links...

The role of the cofilin-actin rod stress response in neurodegenerative diseases uncovers potential new...

Abstract The cofilin-actin rod stress response is an actin cytoskeletal dynamic arrest that occurs in cells under a variety of stress conditions. Upon stress, the...

Sangamo BioSciences And Collaborators Highlight Widening Applications Of ZFP Therapeutics® In Presentations At Major...

Increasing Use of ZFN-Mediated Gene Editing by Gene Therapy Field RICHMOND, Calif., May 21, 2012 /PRNewswire/ -- Sangamo BioSciences, Inc. (Nasdaq: SGMO) announced today that data...

Mitochondrial gene regulators involved in Huntington’s disease pathology

By Andrew Czyzewski 16 July 2012 Sci Transl Med 2012; 4: 142ra97 MedWire News: Researchers have identified two molecules involved in mitochondrial function that appear to be...

News flash: Isis and Roche hope to start Huntington’s gene-silencing trial in first half...

The long-anticipated clinical trial of a drug that could potentially stop Huntington’s disease at its genetic roots and perhaps someday even prevent the disorder...
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Scientists identify brain cells involved in Pavlovian response

UCLA research could help improve understanding of Parkinson’s, Huntington’s and Tourette’s In his famous experiment, Russian scientist Ivan Pavlov rang a bell each time he...

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Sheep Help Scientists Fight Huntington’s Disease

Sheep are helping scientists gain ground against Huntington's disease When University of Cambridge neurobiologist Jenny Morton began working with sheep five years ago, she anticipated...

BioSensics™ Has Received over $2.5M in Grant Funding from the NIH...

BioSensics, a leader in developing wearable sensor technologies for clinical research and medical applications, has received grant funding from the National Institutes of Health...

Raptor Announces Clinical Results With RP103 in Huntington’s Disease Phase 2/3...

NOVATO, Calif., Feb. 20, 2014 (GLOBE NEWSWIRE) -- Raptor Pharmaceutical Corp. (Nasdaq:RPTP) today announced top line results from a planned 18 month analysis of...

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